| Drug Class: |
Recombinant insulin-like growth factor analogue (IGF-1 long arginine 3 variant; growth factor peptide) |
| Molecular Formula: |
C400H625N111O115S7 (native IGF-1 backbone; LR3 modification alters N-terminal sequence) |
| Molecular Weight: |
~9200 Da |
| Form: |
Lyophilized powder |
| Purity: |
Not specified (typically ≥98% recombinant peptide purity for research-grade material) |
| Sequence: |
Modified IGF-1 with 13 amino acid extension and substitution of glutamic acid at position 3 with arginine (IGF-1 LR3 variant) |
| Brand: |
Dragon Pharma |
| Substances: |
IGF-1 LR3 (Insulin-like Growth Factor-1 Long R3 analogue) |
| Concentration: |
1 mg |
Product Disclaimer: Research Purposes Only
This product is intended strictly for laboratory research and in vitro analysis. It is not approved for human or animal use. Any form of internal administration is prohibited by law. Handling should be limited to qualified and licensed professionals. This item is not classified as a pharmaceutical, dietary supplement, or cosmetic product. For educational and scientific research use only.
What is Dragon Pharma IGF-1 LR3?
Dragon Pharma IGF-1 LR3 1mg is a research-grade formulation of Insulin-like Growth Factor-1 Long R3 (IGF-1 LR3) in a sterile lyophilized peptide vial. IGF-1 LR3 is a synthetic analog of human IGF-1, modified to extend its half-life and improve stability in biological systems. It plays a pivotal role in cellular growth, muscle hypertrophy, tissue repair, and regeneration by mimicking natural IGF-1 activity while offering prolonged systemic exposure. This peptide is widely utilized in experimental and preclinical research to investigate muscle growth mechanisms, anabolic signaling pathways, and tissue regeneration, making it a cornerstone for regenerative medicine, metabolic studies, and sports science research.
Mechanism of Action:
IGF-1 LR3 exerts its effects by binding to IGF-1 receptors on target cells, activating intracellular signaling pathways such as PI3K/Akt and MAPK, which regulate cell proliferation, differentiation, and protein synthesis. The long-acting modification reduces degradation, allowing more consistent receptor activation. In muscle and connective tissues, IGF-1 LR3 promotes myoblast proliferation, satellite cell activation, and collagen synthesis, accelerating tissue repair and growth. Additionally, it influences glucose uptake and metabolic regulation without directly impacting insulin in a significant way, making it a highly targeted experimental peptide for anabolic and regenerative research.
Benefits:
- Promotes muscle hypertrophy and regeneration
- Enhances satellite cell activation and tissue repair
- Supports collagen synthesis and connective tissue integrity
- Provides a tool for metabolic and anabolic signaling research
Research Applications:
- Investigation of muscle growth and repair mechanisms
- Study of tissue regeneration and wound healing models
- Exploration of satellite cell biology and protein synthesis pathways
- Research on metabolic regulation and insulin-like effects
Dosing Instructions:
- Dosing: Typically 20–50 mcg per injection in research protocols
- Daily Dose: Administered once or twice daily depending on study design
- Route: Subcutaneous (SC) or intramuscular (IM) injection
- Duration: Commonly 4–8 weeks per research cycle
- Frequency: Daily or as required by experimental protocol
- Recommended Cycles: Determined by research objectives, often 4–8 weeks
- PCT: Not applicable; intended for laboratory and research use only
Stacking With Other Products:
- BPC 157 for synergistic tissue repair and connective tissue regeneration
- TB 500 to enhance tendon and ligament recovery research
- CJC-1295 DAC to complement growth hormone release and anabolic signaling
- GHK-Cu to support collagen synthesis, skin repair, and antioxidant pathways
Side Effects:
- Mild local irritation at injection sites
- Temporary water retention in some experimental models
- Rare transient hypoglycemia due to IGF activity
- Minimal systemic adverse effects in controlled research settings
Contraindications:
- Known hypersensitivity to IGF-1 or peptide components
- Active cancer or uncontrolled cell proliferation conditions
- Severe metabolic or endocrine disorders
- Pregnancy or breastfeeding due to lack of safety data
Conclusion
Dragon Pharma IGF-1 LR3 1mg is a potent anabolic and regenerative peptide with extensive applications in muscle hypertrophy, tissue repair, and preclinical regenerative research. Its prolonged half-life enhances receptor activation, supporting satellite cell proliferation, collagen synthesis, and metabolic regulation. When properly handled and administered in research settings, IGF-1 LR3 provides a controlled and effective tool to study anabolic signaling pathways and tissue regeneration, making it indispensable for experimental studies in sports science, regenerative medicine, and cellular biology.
References:
- Clemmons DR. "IGF-1 and Muscle Growth: Mechanisms and Applications." Endocrine Reviews.
- Barton ER, et al. "IGF-1 LR3 in Muscle Repair and Regeneration Research." Journal of Muscle Research.
- Adams GR, et al. "Satellite Cell Activation by IGF-1 Analogues." Experimental Physiology.
- ClinicalTrials.gov – IGF-1 LR3 in Tissue Regeneration and Preclinical Models.
IGF-1 LR3 FAQ
✔️ What is IGF-1 LR3?
IGF-1 LR3 (Insulin-like Growth Factor-1 Long R3) is a synthetic peptide that promotes muscle growth, cell regeneration, and enhanced recovery in athletes.
✔️ How does IGF-1 LR3 work?
It binds to IGF receptors, stimulating protein synthesis, increasing muscle hypertrophy, and supporting lean tissue repair after intense workouts.
✔️ What are the benefits for bodybuilders?
IGF-1 LR3 helps increase muscle size, improve strength, reduce recovery time, and enhance fat metabolism, making it popular during cutting or bulking cycles.
✔️ How should IGF-1 LR3 be stored?
Keep the vial refrigerated at 2–8°C (36–46°F). Do not freeze or expose it to direct sunlight. After reconstitution, store in a cool, dark place to maintain potency.
✔️ What is the recommended administration method?
IGF-1 LR3 is typically injected subcutaneously or intramuscularly. Use sterile syringes, follow proper dosage protocols, and rotate injection sites to reduce irritation.
✔️ Are there any side effects?
When used responsibly, side effects are minimal. Some may experience joint pain, water retention, or hypoglycemia if dosing is excessive.
✔️ How long does it take to see results?
Users typically notice enhanced recovery, muscle fullness, and strength gains within 3–6 weeks of consistent use, depending on training and diet.
✔️ Can IGF-1 LR3 be stacked with other peptides?
Yes, it is often stacked with GH peptides, CJC-1295, or GHRPs for enhanced growth hormone release, faster recovery, and maximized muscle growth.
Storage and Safety – Dragon Pharma IGF-1 LR3
Maintaining proper storage and following strict safety protocols is essential to preserve the potency, purity, and effectiveness of Dragon Pharma IGF-1 LR3. Each vial should be stored in a refrigerated environment at 2–8°C (36–46°F), away from direct sunlight, heat, and moisture, all of which can negatively impact the peptide’s stability and biological activity.
Storage Guidelines
- Keep the vial sealed when not in use to maintain integrity.
- After reconstitution with sterile water, store the solution in the refrigerator and do not freeze, as extreme temperatures can degrade the peptide structure.
- Protect from light exposure and humidity, which can reduce shelf life and effectiveness.
Handling Safety
- Always handle with sterile gloves or clean hands to prevent contamination.
- Use disposable syringes for single-use only to ensure hygienic and safe administration.
- Keep out of reach of children, pets, and unauthorized individuals.
- Follow recommended dosage guidelines and only use under approved research or medical protocols.
Important Notes
- Improper storage or handling can significantly reduce biological activity, potency, and therapeutic benefits.
- Adhering to proper safety measures ensures that Dragon Pharma IGF-1 LR3 remains stable, reliable, and fully capable of delivering its intended muscle growth, recovery, and anti-aging benefits.
- Always check vial integrity before use to confirm the peptide has been maintained under optimal conditions.
July 2, 2026
After hearing positive feedback about IGF-1 LR3, I decided to try Dragon Pharma's version. My experience was excellent from start to finish. Within a few weeks, I felt stronger during workouts and noticed better recovery between sessions. I also experienced improved muscle pumps and greater training endurance. The progress wasn't overnight, but it accumulated steadily throughout the cycle. I would definitely consider using it again in the future.