| Drug Class: |
Phosphodiesterase type 5 (PDE5) inhibitor; vasodilatory agent |
| Molecular Formula: |
C22H30N6O4S |
| Molecular Weight: |
474.58 g/mol |
| Form: |
Oral tablets |
| Purity: |
Pharmaceutical-grade active substance |
| Brand: |
Dragon Pharma |
| Substances: |
Sildenafil citrate (commonly known as sildenafil) |
| Concentration: |
50 mg |
Product Disclaimer: Research Purposes Only
This product is intended strictly for laboratory research and in vitro analysis. It is not approved for human or animal use. Any form of internal administration is prohibited by law. Handling should be limited to qualified and licensed professionals. This item is not classified as a pharmaceutical, dietary supplement, or cosmetic product. For educational and scientific research use only.
What is Dragon Pharma Viagra (Sildenafil)?
Viagra (Sildenafil) is a phosphodiesterase type‑5 (PDE‑5) inhibitor widely known for its role in improving blood flow by relaxing smooth muscle tissue within blood vessels. Originally developed for cardiovascular research, Sildenafil became widely recognized for its ability to treat erectile dysfunction by enhancing nitric‑oxide‑mediated vasodilation in penile tissue. In research and clinical settings, Viagra (Sildenafil) is also studied for its effects on pulmonary circulation, vascular health, and endothelial function. Its mechanism makes it a valuable compound in studies examining vascular responsiveness, blood flow regulation, and nitric oxide signaling pathways.
Mechanism of Action:
Viagra (Sildenafil) works by selectively inhibiting the enzyme phosphodiesterase‑5 (PDE‑5), which is responsible for breaking down cyclic guanosine monophosphate (cGMP). By preventing cGMP degradation, Sildenafil enhances nitric oxide signaling and promotes relaxation of smooth muscle cells within blood vessels. This process increases blood flow, particularly in the corpus cavernosum of the penis, facilitating improved erectile response during sexual stimulation. In addition, Viagra (Sildenafil) influences pulmonary vascular resistance and endothelial function, which is why it is also studied in pulmonary hypertension and cardiovascular research. Its targeted mechanism allows researchers to investigate vascular physiology, nitric oxide pathways, and circulatory system modulation.
Benefits:
- Improves blood flow through enhanced nitric oxide–mediated vasodilation.
- Supports erectile function by increasing circulation to penile tissue.
- Enhances vascular performance and endothelial responsiveness.
- Provides a model for studying nitric oxide signaling and circulatory physiology.
Research Applications:
- Investigating vascular function and endothelial nitric oxide signaling pathways.
- Studying erectile dysfunction mechanisms and therapeutic interventions.
- Researching pulmonary hypertension and pulmonary vascular resistance.
- Exploring cardiovascular circulation, vasodilation, and blood pressure modulation.
Dosing Instructions:
- Dosing: Viagra (Sildenafil) tablets are taken orally with water, typically before anticipated activity or according to research protocol guidelines.
- Daily Dose: Standard research doses generally range from 25–100 mg depending on the objective and subject response.
- Route: Oral administration via tablet form.
- Duration: Effects typically last 4–6 hours depending on metabolism and dosage.
- Frequency: Usually taken once per day as needed, allowing sufficient time between doses.
- Recommended Cycles: Continuous daily use protocols may be studied for vascular or pulmonary research; otherwise used intermittently as required.
- PCT: Post‑cycle therapy is not required since Sildenafil does not suppress endogenous hormone production.
Stacking With Other Products:
- Tadalafil (Cialis) for comparative PDE‑5 inhibitor research and extended vascular effects.
- L‑Arginine to support nitric oxide production and enhance vasodilation pathways.
- Citrulline Malate for synergistic nitric oxide boosting and improved circulation.
- Testosterone therapy in studies examining sexual health and endocrine interactions.
Side Effects:
- Headache or facial flushing due to increased blood flow.
- Nasal congestion or mild digestive discomfort.
- Temporary visual disturbances such as color perception changes.
- Dizziness or mild drop in blood pressure in sensitive individuals.
Contraindications:
- Use with nitrate medications due to risk of severe blood pressure drop.
- Hypersensitivity to Sildenafil or other PDE‑5 inhibitors.
- Severe cardiovascular conditions where sexual activity is medically restricted.
- Individuals with significant liver or kidney impairment without medical supervision.
Conclusion
Viagra (Sildenafil) remains one of the most recognized and extensively studied PDE‑5 inhibitors for improving blood flow and vascular responsiveness. Its ability to enhance nitric‑oxide‑mediated vasodilation has made it an essential compound in both clinical therapy and experimental cardiovascular research. Beyond its primary use for erectile dysfunction, Sildenafil provides valuable insight into endothelial function, pulmonary circulation, and vascular physiology. When used according to established protocols, Viagra (Sildenafil) demonstrates reliable pharmacological activity with predictable effects on blood vessel relaxation and circulation. Its versatility in research continues to support studies exploring cardiovascular health, pulmonary function, and nitric oxide signaling pathways.
References:
- Goldstein I, et al. "Oral Sildenafil in the Treatment of Erectile Dysfunction." New England Journal of Medicine. 1998;338(20):1397–1404.
- Corbin JD, Francis SH. "Phosphodiesterase‑5 inhibitors and nitric oxide signaling." Journal of Biological Chemistry. 2002;277(4):2793–2796.
- ClinicalTrials.gov Identifier: NCT00000611 – Sildenafil for Pulmonary Hypertension Studies.
- Ghofrani HA, et al. "Sildenafil for Treatment of Lung Circulatory Disorders." Circulation. 2005;111(2):203–210.
Viagra (Sildenafil) – FAQ
✔️ What is Viagra (Sildenafil)?
Viagra is a PDE5 inhibitor used in research to study vascular smooth muscle relaxation, blood flow, and erectile physiology.
✔️ How does Viagra work?
It inhibits phosphodiesterase type-5 (PDE5) in smooth muscle, increasing cGMP levels, which enhances vasodilation and tissue perfusion in experimental models.
✔️ What are the recommended storage conditions?
Store tablets in a cool, dry place at 15–30°C (59–86°F), away from light, heat, and moisture, and keep in the original blister pack or container until use.
✔️ Is Viagra safe for laboratory research?
Yes, when handled according to controlled laboratory protocols, it is safe for preclinical or analytical studies. It is not intended for human consumption.
✔️ Can Viagra be combined with other compounds?
Yes, in research settings, it may be studied alongside other vasodilators, peptides, or metabolic modulators to investigate synergistic effects on vascular function.
✔️ How long is Viagra stable?
Properly stored tablets remain stable until the expiration date. Avoid crushing, splitting, or exposing tablets to moisture or extreme temperatures to maintain full potency.
Storage and Safety – Viagra (Sildenafil)
Proper storage and handling of Viagra (Sildenafil) are essential to maintain its potency, stability, and effectiveness. The tablets should be stored in a cool, dry place at 15–30°C (59–86°F), away from direct sunlight, heat, and moisture, which can degrade the active ingredient. Keep the tablets in their original blister pack or container until use to protect from contamination and environmental factors.
Do not crush or break tablets unless specifically instructed, as this may affect the drug release and efficacy. Keep all tablets out of reach of children and pets. Avoid exposing the product to extreme temperatures or humidity, as it can compromise chemical stability.
Safety precautions include following all research or experimental protocols, wearing gloves if handling multiple tablets, and avoiding accidental ingestion outside controlled studies. Dispose of unused or expired tablets according to pharmaceutical waste guidelines. This product is intended strictly for research and laboratory purposes and is not for human consumption unless under medical supervision.
Summary: Maintaining proper temperature, dryness, and secure storage ensures that Viagra (Sildenafil) retains full efficacy and safety for experimental research, pharmacological studies, or controlled laboratory applications involving phosphodiesterase inhibition and erectile function research.